Review





Similar Products

par4 ap  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc par4 ap
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
Par4 Ap, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pmc12962907-56-22-27?v=Cell+Signaling+Technology+Inc
Average 94 stars, based on 1 article reviews
par4 ap - by Bioz Stars, 2026-06
94/100 stars
  Buy from Supplier
anti par 4 2328s abs  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc anti par 4 2328s abs
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
Anti Par 4 2328s Abs, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pmc12452670__BLOODA_ADV-2025-015796-mmc1-8-12-18?v=Cell+Signaling+Technology+Inc
Average 94 stars, based on 1 article reviews
anti par 4 2328s abs - by Bioz Stars, 2026-06
94/100 stars
  Buy from Supplier
par 4 agonist ay nh2  (Tocris)
93
Tocris par 4 agonist ay nh2
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
Par 4 Agonist Ay Nh2, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pmc12591568-230-9-15?v=Tocris
Average 93 stars, based on 1 article reviews
par 4 agonist ay nh2 - by Bioz Stars, 2026-06
93/100 stars
  Buy from Supplier
4-(2-pyridylazo) resorcinol (par)  (Macklin Inc)
90
Macklin Inc 4-(2-pyridylazo) resorcinol (par)
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
4 (2 Pyridylazo) Resorcinol (Par), supplied by Macklin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pm40490315-28-4-10?v=Macklin+Inc
Average 90 stars, based on 1 article reviews
4-(2-pyridylazo) resorcinol (par) - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier
colorimetric chelator 4-(2-pyridylazo)resorcinol (par)  (Millipore)
90
Millipore colorimetric chelator 4-(2-pyridylazo)resorcinol (par)
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
Colorimetric Chelator 4 (2 Pyridylazo)resorcinol (Par), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pm40513263-73-2-5?v=Millipore
Average 90 stars, based on 1 article reviews
colorimetric chelator 4-(2-pyridylazo)resorcinol (par) - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier
4-(2-pyridylazo)resorcinol (par)  (Thermo Fisher)
90
Thermo Fisher 4-(2-pyridylazo)resorcinol (par)
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
4 (2 Pyridylazo)resorcinol (Par), supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pm40059844-32-1-15?v=Thermo+Fisher
Average 90 stars, based on 1 article reviews
4-(2-pyridylazo)resorcinol (par) - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier
par 4-activating peptide par4-ap, aypgkf-nh 2  (AnaSpec)
90
AnaSpec par 4-activating peptide par4-ap, aypgkf-nh 2
Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , <t>PAR4-AP</t> (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.
Par 4 Activating Peptide Par4 Ap, Aypgkf Nh 2, supplied by AnaSpec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pmc12166811-51-35-40?v=AnaSpec
Average 90 stars, based on 1 article reviews
par 4-activating peptide par4-ap, aypgkf-nh 2 - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier
par4  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc par4
DMEM = Dulbecco's Modified Eagle's Medium; FOXA2 = forkhead box A2; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; H/R = hypoxia/reoxygenation; IgG = immunoglobulin G; NC = negative control; oe = overexpression; <t>PAR4</t> = protease-activated receptor 4; RT-qPCR = reverse transcription quantitative polymerase chain reaction. ** p<0.01, *** p<0.001.
Par4, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/pmc12046306-90-31-34?v=Cell+Signaling+Technology+Inc
Average 94 stars, based on 1 article reviews
par4 - by Bioz Stars, 2026-06
94/100 stars
  Buy from Supplier
4-(2-pyridylazo)resorcinol (par  (Merck & Co)
90
Merck & Co 4-(2-pyridylazo)resorcinol (par
DMEM = Dulbecco's Modified Eagle's Medium; FOXA2 = forkhead box A2; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; H/R = hypoxia/reoxygenation; IgG = immunoglobulin G; NC = negative control; oe = overexpression; <t>PAR4</t> = protease-activated receptor 4; RT-qPCR = reverse transcription quantitative polymerase chain reaction. ** p<0.01, *** p<0.001.
4 (2 Pyridylazo)resorcinol (Par, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/par+4/10__1016_slash_j__idairyj__2024__106113-60-2-27?v=Merck+%26+Co
Average 90 stars, based on 1 article reviews
4-(2-pyridylazo)resorcinol (par - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier

Image Search Results


Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , PAR4-AP (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.

Journal: Frontiers in Pharmacology

Article Title: Role of albumin in regulating platelet function

doi: 10.3389/fphar.2026.1734694

Figure Lengend Snippet: Hypoproteinemia was found to promote platelet activation. (A–E) Wash platelet aggregation in WT, ADR and ADR Albumin mice induced by thrombin (A) , U46619 (B) , PAR4-AP (C) , collagen (D) and ADP (E) (n = 5 independent experimental animals). (F–H) Thrombin (F) , U46619 (G) and PAR4-AP (H) induced integrin αIIbβ3 activation in washed platelets from mice (n = 5 independent experimental animals). (I–K) Thrombin (I) , U46619 (J) and PAR4-AP (K) induced P-selectin release from washed platelets from mice (n = 5 independent experimental animals). (L–O) ATP release from washed platelets in mice was induced by thrombin (L) , U46619 (M) , PAR4-AP (N) and collagen (O) (n = 5 independent experimental animals). (P–R) Wash platelet spreading in mice induced by U46619 (P) , mean spreading area of individual platelets (Q) , and proportion of spreading platelets to total platelets in the field of view (R) (n = 3 independent experimental animals). Differences between groups were assessed by one-way ANOVA followed by Dunnett’s post hoc test. Statistics are presented as mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001.

Article Snippet: Rabbit antibodies against phospho-PKC substrate (2261), phospho-Akt (Ser473) (11E7), Akt (pan) (11E7), PKC alpha (2056), GAPDH (5174), cell lysate buffer (9803), and PAR4-AP (2328) were sourced from Cell Signaling Technology, Inc. (Beverly, MA, United States).

Techniques: Activation Assay

DMEM = Dulbecco's Modified Eagle's Medium; FOXA2 = forkhead box A2; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; H/R = hypoxia/reoxygenation; IgG = immunoglobulin G; NC = negative control; oe = overexpression; PAR4 = protease-activated receptor 4; RT-qPCR = reverse transcription quantitative polymerase chain reaction. ** p<0.01, *** p<0.001.

Journal: Korean Circulation Journal

Article Title: UPF1 Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating SMURF2 -Mediated Ubiquitination Degradation of FOXA2

doi: 10.4070/kcj.2024.0190

Figure Lengend Snippet: DMEM = Dulbecco's Modified Eagle's Medium; FOXA2 = forkhead box A2; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; H/R = hypoxia/reoxygenation; IgG = immunoglobulin G; NC = negative control; oe = overexpression; PAR4 = protease-activated receptor 4; RT-qPCR = reverse transcription quantitative polymerase chain reaction. ** p<0.01, *** p<0.001.

Article Snippet: After 1 hour of blockade with 5% bovine serum albumin, membranes were incubated with antibodies overnight at 4˚C: UPF1 (#12040, Cell Signaling Technology, CST, Danvers, MA, USA), FOXA2 (#8186T, 1:1,000, CST), PAR4 (#2328, 1:1,000, CST), Bax (ab32503, 1:1,000, Abcam, Cambridge, MA, USA), Cleaved caspase-3 (ab184787, 1:1,000, Abcam), SYVN1 (13473-1-AP, 1:1,000, Proteintech, Rosemont, IL, USA), SMURF2 (18038-1-AP, 1:1,000, Proteintech), WW domain containing E3 ubiquitin protein ligase 2 (WWP2; 12197-1-AP, 1:1,000, Proteintech).

Techniques: Modification, Negative Control, Over Expression, Quantitative RT-PCR, Reverse Transcription, Real-time Polymerase Chain Reaction

GAPDH = glyceraldehyde 3-phosphate dehydrogenase; FOXA2 = forkhead box A2; I/R = ischemia/reperfusion; NC = negative control; oe = overexpression; PAR4 = protease-activated receptor 4; SMURF2 = SMAD-specific E3 ubiquitin ligase 2; TTC = tetrazolium chloride; UPF1 = up-frameshift 1. *** p<0.001.

Journal: Korean Circulation Journal

Article Title: UPF1 Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating SMURF2 -Mediated Ubiquitination Degradation of FOXA2

doi: 10.4070/kcj.2024.0190

Figure Lengend Snippet: GAPDH = glyceraldehyde 3-phosphate dehydrogenase; FOXA2 = forkhead box A2; I/R = ischemia/reperfusion; NC = negative control; oe = overexpression; PAR4 = protease-activated receptor 4; SMURF2 = SMAD-specific E3 ubiquitin ligase 2; TTC = tetrazolium chloride; UPF1 = up-frameshift 1. *** p<0.001.

Article Snippet: After 1 hour of blockade with 5% bovine serum albumin, membranes were incubated with antibodies overnight at 4˚C: UPF1 (#12040, Cell Signaling Technology, CST, Danvers, MA, USA), FOXA2 (#8186T, 1:1,000, CST), PAR4 (#2328, 1:1,000, CST), Bax (ab32503, 1:1,000, Abcam, Cambridge, MA, USA), Cleaved caspase-3 (ab184787, 1:1,000, Abcam), SYVN1 (13473-1-AP, 1:1,000, Proteintech, Rosemont, IL, USA), SMURF2 (18038-1-AP, 1:1,000, Proteintech), WW domain containing E3 ubiquitin protein ligase 2 (WWP2; 12197-1-AP, 1:1,000, Proteintech).

Techniques: Negative Control, Over Expression

FOXA2 = forkhead box A2; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; H/R = hypoxia/reoxygenation; NC = negative control; oe = overexpression; PAR4 = protease-activated receptor 4; SMURF2 = SMAD-specific E3 ubiquitin ligase 2; UPF1 = up-frameshift 1. * p<0.05, ** p<0.01, *** p<0.001.

Journal: Korean Circulation Journal

Article Title: UPF1 Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating SMURF2 -Mediated Ubiquitination Degradation of FOXA2

doi: 10.4070/kcj.2024.0190

Figure Lengend Snippet: FOXA2 = forkhead box A2; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; H/R = hypoxia/reoxygenation; NC = negative control; oe = overexpression; PAR4 = protease-activated receptor 4; SMURF2 = SMAD-specific E3 ubiquitin ligase 2; UPF1 = up-frameshift 1. * p<0.05, ** p<0.01, *** p<0.001.

Article Snippet: After 1 hour of blockade with 5% bovine serum albumin, membranes were incubated with antibodies overnight at 4˚C: UPF1 (#12040, Cell Signaling Technology, CST, Danvers, MA, USA), FOXA2 (#8186T, 1:1,000, CST), PAR4 (#2328, 1:1,000, CST), Bax (ab32503, 1:1,000, Abcam, Cambridge, MA, USA), Cleaved caspase-3 (ab184787, 1:1,000, Abcam), SYVN1 (13473-1-AP, 1:1,000, Proteintech, Rosemont, IL, USA), SMURF2 (18038-1-AP, 1:1,000, Proteintech), WW domain containing E3 ubiquitin protein ligase 2 (WWP2; 12197-1-AP, 1:1,000, Proteintech).

Techniques: Negative Control, Over Expression